When a growing life sciences company needed to build and relocate a new research laboratory without slowing ongoing operations, timelines and compliance left no room for error. Bothwell acted as the “missing link” — project managers, mediators, and technical troubleshooters who ensured alignment across stakeholders
What if the key to faster innovation, lower costs, and smarter growth was just one decision away? In a world where agility and expertise set the winners apart, outsourcing biotech engineering talent isn’t just a cost-saving tactic—it’s a strategic edge.
From developing next-gen gene therapies to scaling up novel biologics, the pressure is on for biotechnicians and biochemical engineers.
There are a variety of maintenance strategies to ensure that businesses can start up, operate, retrofit, and shut down. But “run to failure” no longer exists in the active parts of the business world. A light bulb in the middle of nowhere, in an empty building, is one of the few cases where the waste and lack of significant recycling efforts could justify using a run-to-failure approach.
The success of any engineering project hinges on the strength and diversity of skill sets of the team behind it. This post explores why building a multidisciplinary engineering team is critical—and how to do it strategically through targeted recruitment, skill diversity, and a collaborative culture.
With strategic planning, technological innovation, and collaborative efforts, challenges for gene therapy facilities can be overcome.
From fostering a culture of pride and teamwork to upholding integrity and expertise, these values shape our approach, ensuring we empower our clients and consultants to succeed. At Bothwell, we don’t just solve engineering challenges—we build lasting relationships, challenge conventional thinking, and create meaningful impact across the industry.
Bothwell Engineering played a critical role in the successful execution of a $100M facility retrofit and a $300M brownfield expansion for a global Cell & Gene Therapy CDMO. Our expert consultants led the project from construction completion through GMP readiness, ensuring seamless execution across multiple workstreams. This case study highlights how Bothwell’s expertise in Operational Readiness, CQV, and Project Engineering supported the expansion of cutting-edge manufacturing space, enabling the production of life-changing therapies.
Customization plays a pivotal role in enhancing engineering solutions tailored to specific needs. This blog post explores the essence of biotech customization, explaining its significance in driving innovation and efficiency within the industry.
If you're someone who has a technical background, exceptional communication skills, and a desire to help businesses tackle challenging projects, then a career as an engineering consultant may be right for you. Engineering consultants leverage their expertise to provide efficient and effective solutions to clients. However, it’s a competitive field, and you’ll need these characteristics to get and succeed at the top engineering consulting jobs.
Engineering consulting firms play a crucial role in various industries by providing expert advice and support in the planning, design, and execution of engineering projects. Firms like Bothwell Engineering offer a wide range of specialized services, often tailored to meet the specific needs of their clients.
Life Science companies rely on rigorous commissioning and qualification (CQV) programs to succeed today and in the future.
In the life science industry, engineering life cycle documentation is vital to ensure compliance with Good Manufacturing Practice (GMP) regulations. This sector, which encompasses the development and production of biologics, vaccines, and other therapeutic products, operates under stringent regulatory frameworks. Proper documentation throughout the engineering life cycle helps maintain product quality, safety, and efficacy while facilitating regulatory compliance and operational excellence.
Good Manufacturing Practices are a set of regulations and guidelines to ensure the quality, safety, and efficacy of pharmaceutical products. In the biopharmaceutical sector, compliance with GMP is not just a legal requirement; it's a commitment to patient safety and product integrity. This involves rigorous control of processes, materials, and facilities to prevent contamination, mix-ups, and errors. Engineering optimization within this framework helps organizations achieve these goals while minimizing waste and maximizing productivity.
In industries where Good Manufacturing Practices (GMP) are essential—such as pharmaceuticals, biotechnology, food, and cosmetics—equipment maintenance is not just about keeping operations running smoothly. It is also a regulatory requirement that directly impacts product quality and safety. Efficient maintenance strategies are critical for ensuring compliance, minimizing downtime, and enhancing productivity. This blog post will explore key approaches to optimizing GMP equipment maintenance to strike a balance between operational efficiency and regulatory compliance.
Understanding the unique challenges and opportunities within the rapidly evolving Life Sciences landscape is crucial for success. As companies aim to innovate and bring cutting-edge solutions to the market, effective project management becomes vital.
From fostering collaboration among interdisciplinary teams to navigating the quality requirements of creating and working in a cGMP environment, Life Science companies must be equipped with the right strategies to ensure project success. This blog highlights some project management strategies and tips that drive successful outcomes in complex projects.
Are you considering working with a Life Science Consultant?
Here are five facts that highlight what sets Bothwell Engineering apart from its peers:
Proactive KPI Planning: A Guide for Conscientious Project Managers
This blog isn't focused on which KPIs to use. Instead, it emphasizes the importance of identifying the right KPIs and ensuring the project is set up to collect the necessary data from the outset.
In the field of biotechnology, where innovation is at the heart of everything, each stage of a project must be meticulously planned and executed to ensure efficiency and reliability. One crucial stage that significantly impacts both timelines and budgets is commissioning. This process, overseen by a commissioning engineer, plays a major role in the final validation and readiness of biotech facilities and equipment for operational use.
Discover how incorporating Production Opportunity Cost Analysis into your project decision-making process can maximize efficiency, optimize resource allocation, and drive unparalleled project success.
How do we help the term Value Engineering regain its reputation as a good and useful Engineering exercise?
Bothwell can offer a large contingent of experienced personnel to help assess the merits of the value engineering recommendations.
Commissioning personnel play a critical role in ensuring the successful execution and performance of contracts. Learn more about their role in this blog post.
When it comes to large, complex projects, commissioning is an essential activity to ensure the project goals are achieved.
Engineers are unsung heroes behind the scenes, responsible for the design, developing the processes and precision needed to bring life-saving drugs from the lab bench to the patient's bedside.
Congratulations, you've graduated with a degree in engineering! With your hard-earned smarts and the enthusiasm of a fresh graduate, the next step in your professional journey is just ahead.
Contract engineers at Bothwell Engineering play a pivotal role in helping companies successfully execute short-term projects. Our expertise and specialized skill sets can be the missing piece needed to bridge the gap between your project's requirements and your team's capabilities.
With the pressure for gene and cell therapy clinical settings to stay current and safe comes a need for engineering consulting companies.
The leadership team at Bothwell Engineering Inc. are intimately familiar with the journey of climbing the engineering ladder. Each member leaped independent consulting. Despite holding well-paying and stable positions, they felt a deep desire for increased flexibility, variety, and daily challenges in their work.
At Bothwell Engineering, we understand the challenges facing biotech and pharmaceutical companies in their quest to stay ahead of the competition.
When your company is preparing to roll out a new pharmaceutical product, you need access to the best talent available to fill the roles of product engineers. We’ll go over three important questions to ask in this article that can help you get a basic sense of whether or not a given candidate will make for a good fit, including their experience in similar roles, the types of products they’ve worked on, and the expectations they have of their work and position on your team.
Gene therapies offer incredible promise for treating diseases, but bringing these complex therapies to market comes with unique challenges.
Expanding an existing manufacturing facility is a complex undertaking filled with many steps and key decisions—Bothwell Engineering is here to help.
Are you looking to gain a competitive edge in the marketplace? Working with an engineering consulting company may be the answer you've been searching for.
In today's business world, it is essential for companies to remain competitive and efficient. One way to achieve this is by partnering with an engineering consultant.
As the biotech industry continues to grow and evolve, the role of a biotech process engineer has become increasingly important. These professionals are responsible for designing, developing, and implementing processes to produce biotech products such as pharmaceuticals, vaccines, and biologics.
Equipment procurement is integral to modern-day businesses, particularly in the manufacturing and production sectors. However, it is not just the procurement of equipment that is important, but also the process of ensuring that the purchased equipment is fit for purpose.
As a leading chemical engineering consulting firm, Bothwell Engineering is well-equipped to handle a wide range of projects for clients in the biotech, pharmaceutical, cell and gene therapy industries.
When it comes to biotech and pharmaceuticals, hiring contracted engineers can be an excellent way to get the specialized skills and expertise you need to tackle a specific project or challenge.
As a premier provider of talent to leading biotech companies, we acknowledge the pivotal importance of curating project teams composed of highly skilled and seasoned professionals. The success of every project is intricately tied to the combined expertise and proficiency demonstrated by its team members.
In biotechnology, a company can’t afford to make mistakes. If a production run occurs that doesn’t follow the safety guidelines exactly, it can contaminate the entire batch, endanger consumers, and result in violations and fines.
Industries have implemented a number of safeguard measures when it comes to the production and manufacturing of certain types of goods. These protocols are designed to protect consumers from faulty products and provide liability coverage to the manufacturers.
If you are an industry leader in clinical or commercial enterprises, such as biotech, pharmaceuticals, and cell and gene therapy, then you understand how important the commissioning process is.
It can be difficult to understand why you should invest time, money, and resources into consulting with a pharmaceutical manufacturing process engineer.
When it comes to designing a facility for your biotech, pharmaceutical, cell, or gene therapy business, you want to make sure that everything is done correctly the first time.
When leaders decide to expand their manufacturing firms, they should hire experts to help develop a business plan that allows the flexibility necessary to grow.
A pharmaceutical engineer must be consulted continuously through the planning and execution of a manufacturing plant expansion.
Biotechnology is a field that seeks to improve lives by tapping into biological processes to develop and produce medicines that fight against diseases, protect the environment, and utilize clean energy. When used well, biotechnology can help save lives around the world and promote food sustainability and productivity.
Within the engineering industry, the role of a commissioning engineer is essential across every sector. It’s an integral position combining theory with practice and provides a dynamic working experience.
Engineering consulting firms may provide inclusive services. But other consultants specialize in specific areas — like structural, geotechnical, and environmental. Typically, the necessity for engineering services is based on the nature of a project and the owner's capability. The services provided by the consultant or firm add value to the project and can improve its quality overall.
From sustainable agriculture to improved healthcare and medicine, here are all the most recent innovations in biotech engineering.
After graduating UNH with a bachelors in Chemical Engineering, Alec reflects on his first year in biotech.
Choosing the right engineering consulting firm for your next project can mean the difference between achieving your goals and falling behind the competition. Here's what makes Bothwell Engineering different.
Your capital expenditures are an essential aspect of running a successful company but mismanaged or unscrutinized, they can slowly erode your profit margin. CapEx consulting helps companies understand their expenses and plan for future projects.
Have you recently graduated from an engineering program? Obtaining a degree in this field is a major accomplishment in itself. New graduates do however, often struggle to determine their next steps upon completion of their studies.
In this blog post, you’ll read four tips from a MA staffing agency providing skilled engineers to some of the nation’s top biomedical organizations for the projects putting revolutionary new treatments and services into the market.
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